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Democratic lawmakers and activists are urging the justice to step down in time to allow a narrow Democratic majority in the Senate to confirm a replacement.
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There are two schools of thought: either the right to abortion will be systemically hollowed out, leaving it a right on paper only, or Roe will be overturned.
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A Pennsylvania county asked the new justice to disqualify herself because her nomination and confirmation is "unprecedented" and linked, by Trump, to his own reelection. It later reversed itself.
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The Senate Judiciary Committee held confirmation hearings for Judge Amy Coney Barrett, President Trump's Supreme Court nominee, this week.
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Thursday was the fourth and final day hearings for President Trump's nominee. Next up in the process is the committee vote on Oct. 22.
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Questioned by Sen. Amy Klobuchar, Barrett also said scholars "say that doesn't mean that Roe should be overruled, but descriptively it does mean that it's not a case that everyone has accepted."
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Amy Coney Barrett's Supreme Court confirmation hearing is moving ahead under exceedingly unusual circumstances, with Election Day looming and a coronavirus outbreak still roiling Washington.
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Separately, President Trump's nominee to fill the Supreme Court seat made vacant by the death of Justice Ruth Bader Ginsburg tested negative for the coronavirus, a White House spokesman says.
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New Jersey Gov. Phil Murphy is backing legislation designed to codify Roe — the 1973 decision that legalized abortion nationwide — in state law and expand abortion access.
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The focus on the court could help energize conservatives in key states. Progressives are fired up, too — immediately after Saturday's announcement, Democrats tied Barrett to a fight for health care.