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U.S. and Iranian negotiators met separately on Wednesday with Qatari and Pakistani mediators, with "positive progress made," and they agreed to continue discussions, host Qatar said.

NPR's Ayesha Rascoe talks to Joan Kautz of Ironstone Vineyards, a winery in California, about the impact of Canadian tariffs on the U.S. alcohol industry.

We look at recent upheaval in Nepal, where Gen Z protesters toppled the government, and put the country's first female prime minister in power.

Venezuelan President Nicolas Maduro arrived in New York City to face criminal charges. There are now fears of a power vacuum in the country as President Trump says the U.S. will "run" the nation.

Chileans head to the polls on Sunday, and an arch-conservative pledging mass migrant expulsions is strongly favored over his leftist opponent.

The volcanologist on the island of Vanuatu who walks barefoot over cooled lava fields tells NPR's Don Gonyea how to see nature at its most primeval.

The FIFA World Cup is thought to bring an economic windfall to the cities and regions where games will be played during four weeks this summer. How true is that?

The Centers for Disease Control and Prevention will be facing a huge leadership vacuum, as Director Susan Monarez is forced out by RFK Jr. and the Trump administration.

NASA wants to land Artemis astronauts on the moon in 2027, but the scientific instruments they'll bring must be tested on Earth. The best place to do that is a mile-wide meteorite crater in Arizona.

NPR's Michel Martin speaks with Maine Secretary of State Shenna Bellows about her run to replace Graham Platner in the Maine Senate race.