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The jackpot for Wednesday's Powerball Lottery is worth at least $280 million. The game is played in 23 states and the District of Columbia, and some people are driving for hours to reach spots where they can buy tickets. NPR's Howard Berkes reports.

Health officials in Maine plan emergency meetings Thursday in response to a Tuesday court decision that could shut down a program that helps lower-income people buy prescription drugs. NPR's Joanne Silberner reports.

The Powerball jackpot is expected to hit nearly $300 million for Wednesday night's drawing. Some of the 23 states offering the giant lottery game are selling more than 1,000 tickets a minute. NPR's Neda Ulaby reports.

Business for cruise lines remains about the same despite recent virus outbreaks on ships. Statistics show that illnesses on cruise ships have declined over the past decade. NPR's Madeleine Brand reports.

NPR's John Ydstie reports on a shakeup of the Bush administration's economic team. Adviser Lawrence Lindsey and Treasury Secretary Paul O'Neill both have announced their resignations. The president is expected to name a new Treasury secretary quickly, according to the White House, and to outline a new economic plan that will include tax cuts.

Some FBI officials are privately upbraiding staff for moving too slowly on a reorganization following the Sept. 11 attacks. Meanwhile, Congress wants to know -- is the FBI ready to fight the war on terror? NPR's Larry Abramson reports.

The United States proposes a ban on imports of Beluga caviar due to over-harvesting in the Caspian Sea, and may put Beluga fish on the endangered species list to stiffen penalties for smugglers. NPR's Eric Niiler reports.

A 42-year-old man living in a 400-year-old oak tree in a Los Angeles suburb focuses a community-wide debate over suburban development. Alex Cohen of member station KQED reports.

Karl Rove, President Bush's top political adviser, plays a pivotal role in both policy and politics. He has gotten credit for the Republican victories in the midterm elections and for the president's high popularity ratings. NPR's Don Gonyea reports.

The Kennedy Center 2002 Honors awards this evening in Washington. Chita Rivera is one of the five recipients, as are James Earl Jones and Elizabeth Taylor. The original Anita in West Side Story, Rivera has spent five decades on the stage and shows no sign of stopping. Kim Kokich reports.