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The investigation into the space shuttle Columbia disaster starts with a focus on a piece of foam insulation that fell off the shuttle's fuel tank and hit its left wing during launch. Columbia broke apart upon re-entry Saturday, killing all seven astronauts aboard. NPR's Joe Palca reports on the first stages of the probe.

A 32-year-old Chicago man is in custody, accused of running a child prostitution ring in five Midwestern states. Authorities say he lured girls -- many of them runaways -- with offers of free jewelry, then held them hostage and made them perform sex acts. Shirley Jahad of Chicago Public Radio reports.

The United States lost nearly one million manufacturing jobs in 2002, but the foreign-car industry continues to grow. Foreign automakers work to build or expand a half-dozen U.S. plants primarily in the Deep South, where the cost of labor is relatively low. NPR's Adam Hochberg reports.

A new book about Howard Lutnick, the CEO of Cantor Fitzgerald, shows the personal and financial damage the Sept. 11 attacks caused the company. On Top of the World discusses how the brokerage firm survived after losing most of its employees in the terrorist attacks. NPR's Juan Williams reports.

North and South Korean officials meet in Seoul for talks on economic cooperation, but discussions are overshadowed by concerns about North Korea's nuclear weapons program. Meanwhile, U.S. envoy John Bolton says he expects the U.N. to begin discussions on the standoff by week's end. NPR's Eric Weiner reports.

When international politics mixes with business, the course of commerce can get complicated. Americans negotiating a deal in England may find themselves defending their nation's foreign policy, or German companies may find it tougher dealing with U.S. firms because of their nation's stance against the Bush administration's plans for action in Iraq. NPR's Chris Arnold reports on how conducting foreign policy interacts with conducting business.

As NASA officials study data and debris from space shuttle Columbia, the initial focus is on an accident at liftoff that may have caused a chain of problems that led to catastrophe. But experts say little could have been done to rescue the ship, even if launch problems had been considered a threat to the mission. NPR's Larry Abramson reports.

The Pentagon puts bombers on alert for possible deployment near North Korea. The apparent message is that the Bush administration is not too distracted by Iraq to respond to a threat on the Korean peninsula. But the administration says it's committed to a diplomatic solution to North Korea's renewed pursuit of nuclear weapons. NPR's Michele Kelemen reports.

NASA is exploring several theories about what could have caused the break-up of the space shuttle Columbia. One likely cause also is one of the most difficult to prove -- that the space shuttle was hit by a piece of debris in orbit. NPR's Richard Harris reports.

The White House and Congress react to North Korea's suggestion it might launch pre-emptive attacks should it feel threatened by the United States. The administration calls the threat "saber rattling." But senior Democrats in the Senate demand the situation be treated as a crisis. NPR's David Welna reports.