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The first Republican presidential primary debate is this Wednesday at 9 p.m. ET. Let us know what you want to know as the candidates take the stage.

A winning ticket has been sold in Los Angeles for the Powerball jackpot worth an estimated $1.08 billion, the sixth largest in U.S. history and the 3rd largest in the history of the game.

President Bush called on Congress to extend his big tax cuts, which otherwise expire in 2010. Unless Congress acts, Bush said, most of the tax relief Congress and the White House have delivered during his two terms will be taken away.

Myron Rolle, the starting strong safety for the Florida State Seminoles, has been awarded the Rhodes scholarship to study at Oxford University. The pre-med student had to miss part of Saturday's game against Maryland because he was being interviewed for the scholarship.

The Justice Department's inspector general has told lawmakers that he is investigating whether one of the agency's lawyers was dismissed over a rumor about her sexual orientation. The inquiry is part of a larger examination of personnel practices under former Attorney General Alberto Gonzales.

Over the course of the summer, we're sailing with Captain Fatty Goodlander, editor-at-large of Cruising World magazine. He's sailing the Pacific Ocean now and sends a communique from aboard his sailboat about his favorite watery destinations: two atolls in the middle of the Pacific.

Many listeners responded angrily to the report Tuesday on how law enforcement is preparing for a spike in white supremacist activity if Barack Obama becomes president.

Legendary folk singer and activist Pete Seeger, who turns 90 years old today, leaves us with a few parting words.

NPR's Scott Simon speaks with Pat Benatar and her husband Neil Giraldo about their 35 years as a music-business power couple.

Most hospitals make little effort to screen patients for tobacco use or to help smokers kick the habit permanently. That's a missed opportunity. Starting this month, though, hospitals can choose to adopt tobacco-cessation measures to help them comply with accreditation standards.